Atovaquone is a naphthalene compound with proven efficacy against Pneumocystis spp fungi and certain protozoa such as Toxoplasma and haemoplasmas.

This drug appears effective against Toxoplasma-induce choroidoretinitis^[1].

Recommended doses in cats is 13.3 mg/kg with fatty meal orally every 8 hours for 21 days^[2]. It appears superior to imidocarb against haemoplasma parasites.

Agaisnt haemoplasmas, it is best used in combination – atovaquone (15 mg/kg p.o. q8h) and azithromycin (10 mg/kg p.o. q24h)^[3].

References

1. ↑ Winterhalter S et al (2010) Does atovaquone prolong the disease-free interval of toxoplasmic retinochoroiditis? Graefes Arch Clin Exp Ophthalmol 248(8):1187-1192
2. ↑ Rand, J (2006) Problem-based feline medicine. Saunders Elsevier, Sydney
3. ↑ Cohn LA et al (2011) Efficacy of atovaquone and azithromycin or imidocarb dipropionate in cats with acute cytauxzoonosis. J Vet Intern Med 25(1):55-60