There are many viruses which infect felidae, some of which cause overt clinical disease while others are asymptomatic.
The properties of viruses which affect cats are not unique and conform to viruses affecting most other mammalian species.
| Virus | Disease | Viral Group | Classification |
| Astrovirus | Diarrhoea | ssRNA | Astroviridae |
| Borna disease virus | Cat staggers | ssRNA | Borna virus |
| Calicivirus (FCV) | Cat Flu | ssRNA | Caliciviridae |
| Coronavirus (FCoV) | Feline infectious peritonitis (FIP) | ssRNA | Coronaviridae |
| Foamy virus (FeFV) | Feline foamy virus disease (nee Feline syncytial virus) | ssRNA | Spumavirus |
| Herpes virus (FHV-1) | Cat Flu | dsDNA | Herpesviridae |
| Feline immunodeficiency virus (FIV) | Cat AIDS | ssRNA | Lentivirus |
| Feline leukaemia virus (FeLV) | Feline leukemia | ssRNA | Retroviridae |
| Panleucopenia (Parvo) virus (FPV) | Feline Panleucopenia | ssDNA | Parvoviridae |
| Influenza virus (H1N1) | Flu-like symptoms, sudden death | ssRNA | Influenza virus |
| Papillomavirus (FPV-1) | Papilloma | dsDNA | Papillomaviridae |
| Parapox virus | Cutaneous ecthyma | dsDNA | Poxviridae |
| Pox virus infection | Feline pox | dsDNA | Poxviridae |
| Pseudorabies | pseudorabies | dsDNA | Herpesviridae |
| Rotavirus infection | Diarrhoea | dsRNA | Reoviridae |
| Sarcoma virus (FeSV) | Feline sarcoma | ssRNA | Retroviridae |
| Spongiform encephalopathy virus (FSE) | Spongiform encephalopathy | FSE prion | |
| Swine flu (H5N1) | ‘Swine flu’-like disease | ssRNA | Orthomyxoviridae |
| Lyssavirus | Rabies | ssRNA | Rhabdoviridae |